Сhronic toxicity testing complex phytopoliextraction of sedative action
نویسندگان
چکیده
منابع مشابه
Comparative Action of Sedative Hypnotics on Neurophysiology of Sleep
In spite of tremendous advances in medical science, sleep has not been understood completely. The causes for many of parasomnias are still not evident. Even then these parasomnias are treated with different drugs, one of the major groups among them being sedative hypnotics. The use of sedative hypnotics are always associated with adverse effect, and there is many a times loss of the normal slee...
متن کاملDexmedetomidine: Sedative and Neuroprotective Mechanisms of Action and New Developments
Dexmedetomidine, the D-enantiomer of medetomidine, is among the most potent sedative drugs known. It is also one of the best understood in terms of its molecular and cellular mechanisms. Its sedative (and probably its neuroprotective) effects are mediated by subtype A of the α2 adrenergic receptor, a G-protein-coupled receptor. Acting as an agonist at this receptor, dexmedetomidine causes numer...
متن کاملCortical glutamatergic neurons mediate the motor sedative action of diazepam.
The neuronal circuits mediating the sedative action of diazepam are unknown. Although the motor-depressant action of diazepam is suppressed in alpha1(H101R) homozygous knockin mice expressing diazepam-insensitive alpha1-GABA(A) receptors, global alpha1-knockout mice show greater motor sedation with diazepam. To clarify this paradox, attributed to compensatory up-regulation of the alpha2 and alp...
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ژورنال
عنوان ژورنال: Farmatsevtychnyi zhurnal
سال: 2018
ISSN: 0367-3057
DOI: 10.32352/0367-3057.5-6.17.05